Chicken Cordon Bleu Biscuit Casserole is a delicious twist on the traditional French‑inspired dish. This hearty casserole layers tender pieces of chicken, ham, creamy Alfredo sauce, and shredded Swiss cheese among fluffy biscuit pieces.
Best of all, it comes together in one pan with minimal effort. That is why it is the perfect dinner recipe on a busy weeknight. However, it is also elegant enough to serve for Sunday supper.
However, there is nothing fancy about this recipe, it is just a new take on comfort food. Best of all, the ingredients are easy to find and you may even have some of them in your fridge, freezer or pantry.

Why This Chicken Cordon Bleu Biscuit Casserole Is A Favorite
- Simple ingredients, big flavor: With refrigerated biscuits, jarred Alfredo sauce, Swiss cheese, chicken, ham, garlic powder, and garlic salt, this casserole has a ton of flavor.
- Minimal prep, maximum comfort: No pounding chicken, no breading, no complicated steps – just toss everything together and then let it bake.
- Versatile meal: It works equally well as a quick weeknight meal or a special occasion dinner, and leftovers reheat beautifully.
- Right‑sized comfort: Made in an 8×8‑inch dish, it’s perfect for two to four servings without a massive amount of leftovers.
What Type of Chicken Works Best?
For your chicken cordon bleu biscuit casserole, any cooked and shredded chicken will work in this recipe. Great options include:
- Rotisserie chicken: Tender, flavorful, and effortlessly shredded.
- Leftover grilled or roasted chicken breasts or thighs: Shred after cooling.
- Poached or boiled chicken: Cooked simply with salt and pepper, then shredded.

Which Type Of Ham Should You Use?
Similarly, you can use:
- Deli ham (shredded or thinly chopped) – easy to handle and subtle in flavor.
- Leftover ham steak (diced) – adds a firmer chew and depth of taste.
- Pre‑diced ham from the grocery deli section – convenient and mild flavor.
Each variety lends a little bit of different texture but provides that classic chicken cordon bleu taste.
How It Compares to a Classic Cordon Bleu Casserole
If you love the flavors of my Chicken Cordon Bleu Casserole, you’ll appreciate how this biscuit version offers a different spin on the same flavor concept. That recipe uses cooked chicken, diced ham, sour cream, cream of chicken soup, mustard, crackers, and pasta – then tops it with buttery crackers before baking in an 8×8 dish.
However, in this casserole recipe, biscuits replace the paste and crackers. Then the Alfredo sauce is a swap for sour cream and condensed soup, but in both versions, you still get all the classic flavors.
They both are simple recipes take that provide that same comfort food feel without a lot of work.

More Reasons to Make This Chicken Cordon Bleu Biscuit Casserole
- Perfect refrigerator/freezer rescue: Use up leftover chicken or frozen ham effortlessly.
- Kid-friendly crowd-pleaser: Cheese, tender chicken, and biscuits are always easy to enjoy.
- Meal prep winner: Assemble ahead, refrigerate, then bake when ready.
- Leftovers are welcome: Store in an airtight container, reheat in a 350 °F oven or microwave until warmed through.
Perfect Occasions for This Dish
- Weeknight dinners: Quick prep, minimal steps, satisfying flavor.
- Sunday gatherings: Serve with a crisp green salad or steamed veggies for an easy but elegant meal.
- Casual get‑togethers: Easy to warm and serve.
- Cooking for two: The 8×8 dish size yields just the right amount without too many leftovers.
Chicken Cordon Bleu Biscuit Casserole Recipe
*A printable recipe card is located at the bottom of this article which contains the specific measurements, temperatures and cook times. However, continue reading below to learn about more helpful tips about this specific recipe.
INGREDIENTS
- 4 Grands biscuits
- 1 cup cooked and shredded chicken
- 3/4 cup deli ham, shredded or diced
- 1 cup Swiss cheese, shredded
- 8 oz Alfredo sauce
- ¼ tsp garlic powder
- ¼ tsp garlic salt
- ½ cup Swiss cheese (for topping)
INSTRUCTIONS
Preheat oven to 375°F (190°C).
1. Cut each biscuit into 6 pieces and then place the pieces in a large bowl.
2. Add Alfredo sauce, garlic powder, and garlic salt. Toss until biscuit pieces are evenly coated.
3. Add the cooked chicken, ham, and 1 cup of shredded Swiss cheese to the bowl and then toss to combine.
4. Spray an 8×8-inch baking dish with non-stick cooking spray.
5. Pour the mixture into the baking dish and then spread evenly. Then top with the remaining ½ cup of cheese.

6. Bake for 30–35 minutes, or until the biscuits are fully cooked and golden brown on top. Let it rest a few minutes before serving.
Cooking Tips for The Best Chicken Cordon Bleu Biscuit Casserole
- Dice or shred evenly: This will ensure every bite has balanced chicken, ham, biscuits, and cheese.
- Use scissors to cut biscuits: Fast, clean, and easy way to make even pieces.
- Spray the dish well: Prevents sticking, especially with gooey cheese.
- Rest after baking: Helps the casserole set and makes it easier to slice.
- Customize sauce ratio: If you prefer a saucier bake, add a splash more Alfredo sauce.
Recipe Variations & Add‑In Ideas
- Swap out the cheese: Try mozzarella or provolone if you prefer a milder melt.
- Add veggies: Stir in chopped broccoli, peas, or mushrooms for color and nutrition.
- Spice it up: Add a pinch of black pepper, Italian seasoning, or red pepper flakes for a subtle kick.
- Make it gluten‑free: Use gluten‑free biscuits and check your Alfredo sauce for GF labeling.

This chicken cordon bleu biscuit casserole is a recipe you’ll turn to again and again. It’s easy to make, easy to customize and universally satisfying.
Whether you’re looking for the ultimate comfort food meal or looking to make an easy dinner recipe this dish never disappoints.
Enjoy! Mary
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Chicken Cordon Bleu Biscuit Casserole
Chicken cordon bleu biscuit casserole is an easy, cheesy dinner recipe perfect for a busy weeknight.
Ingredients
- 4 refrigerated Grands biscuits
- ½ jar Alfredo sauce (about 8 oz)
- ¼ tsp garlic powder
- ¼ tsp garlic salt
- 1 cup cooked, shredded or diced chicken
- 3/4 cup deli or leftover ham, shredded or diced
- 1 ½ cups shredded Swiss cheese, divided
Instructions
- Preheat oven to 375°F.
- Cut each biscuit into 6 pieces and place in a large bowl.
- Toss with Alfredo sauce, garlic powder, and garlic salt.
- Add chicken, ham, and 1 cup Swiss cheese. Mix until evenly coated.
- Spray an 8x8-inch baking dish with non-stick spray.
- Spread biscuit mixture in dish and top with remaining 1/2 cup of cheese.
- Bake for 30–35 minutes or until biscuits are cooked through and golden.
- Let sit 5 minutes before serving.
Notes
Recipe provided by iCookfortwo.com
Nutrition Information
Yield 4 Serving Size 1Amount Per Serving Calories 486Total Fat 27gSaturated Fat 12gTrans Fat 2gUnsaturated Fat 12gCholesterol 100mgSodium 1109mgCarbohydrates 30gFiber 0gSugar 5gProtein 31g
Nutritional Information is to be used as a general guideline only . Nutritional calculations will vary from the types and brands of the products used.